Doxycycline (Doxy) PEP and PrEP

As we receive new and up-to-date information about Doxycycline, we are committed to keeping this content current. We appreciate your understanding and encourage you to check back periodically for the latest updates.

What is Doxy?

Doxy, short for Doxycycline, is an antibiotic used to treat various bacterial infections, including sexually transmitted infections (STIs) such as chlamydia and syphilis.

What Is Doxy PEP and Doxy PrEP ? 

Doxycycline used as post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP) are tools that can prevent infection.

When taken before or after coming into contact with a pathogen (like a virus or bacteria), they can decrease a person’s chances of developing infection.

In our context, PEP involves taking medication after sex where we might come into contact with STIs.

PrEP involves taking medication regularly so it is already in our system when we come into contact with STIs.

Is it Available Yet? 

As of December 1, 2023, post exposure prophylaxis doxycycline (doxy PEP) is available at no cost for some folks accessing HIV PrEP though the provincial HIV PrEP program offered by the BC Centre for Excellence (BC-CfE).

Persons meeting all of the following criteria are eligible to access Doxycycline for PEP through BC-CfE:

  • Current participant of the BC-CfE HIV Treatment Program or the HIV PrEP Program, and
  • Identifies as gay, bisexual or other man who has sex with men, or transgender woman, and
  • Is at increased risk of B-STI as indicated either by having a history of B-STI such as syphilis, chlamydia, or gonorrhea within the past year, or being clinically assessed as being at increased risk
  • Current BC resident with BC Medical Services Plan coverage or Interim Federal Health coverage

For further information, contact the BC-CfE Drug Treatment Program office at 604-806-8515.

Other Ways to Access Doxy 

Some people have access to Doxycycline for PEP and/or PrEP because they are participating in research about Doxy PEP and/or PrEP. The DISCO study is comparing Doxy PEP to Doxy PrEP in participants across Canadian urban centres, including Vancouver.

If you are interested in participating in the DISCO study and want to learn more, visit:

HIM honours the xʷməθkwəy̓əm (Musqueam), Skwxwú7mesh (Squamish), and səlil̓ilw̓ətaʔɬ (Tsleil-Waututh) Nations, and the territories of many nations on the west coast of Turtle Island, on whose unceded and stolen land we live and work. As uninvited inhabitants, we acknowledge that this space is and always will be Indigenous land.

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